Emscripten

Wasmtime

bytecodealliance/wasmtime

Popular

Bytecode Alliance's fast, secure, standards-first Wasm runtime and reference for WASI and components.

wasm-bindgen

wasm-bindgen/wasm-bindgen

Popular

Facilitates high-level interop between Rust-compiled Wasm and JavaScript; now in its own GitHub org.

Wasmer

wasmerio/wasmer

Wasm runtime with WASIX, a package registry and Edge hosting, embeddable in many languages.

WasmEdge

WasmEdge/WasmEdge

CNCF lightweight Wasm runtime for cloud-native, edge and AI inference workloads.

wazero

wazero/wazero

Zero-dependency WebAssembly runtime written in pure Go, no cgo required.

wasm-pack

wasm-bindgen/wasm-pack

Builds Rust-generated Wasm into npm-ready packages; maintained under the wasm-bindgen org.

AssemblyScript

AssemblyScript/assemblyscript

TypeScript-like language that compiles directly to WebAssembly.

Extism

extism/extism

Cross-language framework for building Wasm-based plugin systems into apps.

Spin

spinframework/spin

Rising

CNCF framework for building and running WebAssembly serverless apps; originated at Fermyon.