Blender

Aseprite

aseprite/aseprite

Popular

Popular pixel-art and sprite-animation editor; source-available with paid binaries.

Adobe Substance 3D

adobe.com

Popular

Adobe's industry-standard texturing and material suite (Painter, Designer, Sampler).

Krita

KDE/krita

Free, open-source digital painting app for concept art, textures and 2D animation.

Tiled

mapeditor/tiled

Flexible, free tilemap and level editor with export to most 2D engines.

LDtk

deepnight/ldtk

Modern 2D level editor from the Dead Cells director, with auto-tiling and typed entities.

Blockbench

JannisX11/blockbench

Free low-poly 3D model editor with pixel-art texturing, popular for Minecraft and indie games.

Pixelorama

Orama-Interactive/Pixelorama

Free, open-source pixel-art editor built with Godot.

Material Maker

RodZill4/material-maker

Node-based procedural texture and material authoring tool built on Godot.

TrenchBroom

TrenchBroom/TrenchBroom

Modern brush-based level editor for Quake-style maps, also used with Godot and other engines.