Anthropic Python SDK

OpenAI Python SDK

openai/openai-python

Popular

Official Python client for OpenAI's Responses, Chat Completions, Realtime and embeddings APIs.

OpenAI Node SDK

openai/openai-node

Popular

Official TypeScript/JavaScript client for the OpenAI API; also the de facto client for OpenAI-compatible endpoints.

Anthropic TypeScript SDK

anthropics/anthropic-sdk-typescript

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Official TypeScript client for the Claude API, used in Node, Deno, Bun and edge runtimes.

Google Gen AI Python SDK

googleapis/python-genai

Unified Python SDK for Gemini models via the Gemini Developer API and Vertex AI; replaces google-generativeai.

Google Gen AI JS SDK

googleapis/js-genai

Official TypeScript/JavaScript SDK for Gemini models on the Gemini API and Vertex AI.

Vercel AI SDK

vercel/ai

TrendingPopular

TypeScript toolkit for LLM apps with provider-agnostic streaming, tool calls and React/Vue/Svelte chat hooks.

LiteLLM

BerriAI/litellm

Popular

Python SDK and proxy server that calls 100+ LLM providers through the OpenAI format, with budgets and fallbacks.

OpenRouter

openrouter.ai

Trending

Hosted API that routes one OpenAI-compatible endpoint to hundreds of models across providers with unified billing.

Portkey AI Gateway

Portkey-AI/gateway

Open-source LLM gateway with routing, retries, caching and guardrails across 200+ models.